CSIRO has commenced the first stage of testing potential vaccines for COVID-19. The testing, expected to take three months, is underway at the Australian Animal Health Laboratory in Geelong.
To prepare for disease outbreaks, last year CSIRO partnered with the Coalition for Epidemic Preparedness Innovations (CEPI), a global group that aims to derail epidemics by speeding up the development of vaccines.
In January, CEPI engaged CSIRO to start working on the virus SARS CoV-2, which causes the disease COVID-19. In consultation with the World Health Organisation, CEPI has identified vaccine candidates from The University of Oxford (UK) and Inovio Pharmaceuticals Inc. (US) to undergo the first pre-clinical trials at CSIRO, with further candidates likely to follow.
The latest milestone builds on CSIRO’s growing work to tackle COVID-19, which has included scaling up other potential vaccine candidates at its biologics production facility in Melbourne.
CSIRO Chief Executive, Dr Larry Marshall said: “Beginning vaccine candidate testing at CSIRO is a critical milestone in the fight against COVID-19, made possible by collaboration both within Australia and across the globe.”
“CSIRO researchers are working around-the-clock to combat this disease which is affecting so many – whether it’s at the Australian Animal Health Laboratory (AAHL) or at our state-of-the-art biologics manufacturing facility – we will keep working until this viral enemy is defeated,” Dr Marshall said.
CSIRO is testing the COVID-19 vaccine candidates for efficacy, but also evaluating the best way to give the vaccine for better protection, including an intra-muscular injection and innovative approaches like a nasal spray.
Professor Trevor Drew OBE, is Director of AAHL and leading CSIRO’s COVID-19 virus and vaccine work.
“We have been studying SARS CoV-2 since January and getting ready to test the first vaccine candidates as soon as they are available,” Professor Drew said.
“We are carefully balancing operating at speed with the critical need for safety in response to this global public health emergency.”
CSIRO has a long history of developing and testing vaccines since the opening of the AAHL in 1985. It is the only high biocontainment facility in the southern hemisphere working with highly dangerous and exotic pathogens, including diseases that transfer from animals to people.
Dr Marshall said: “Tackling disease and supporting better health outcomes takes a one-health approach.”
“In 2016 CSIRO created the Health and Biosecurity research group who work with our scientists at AAHL to tackle our national and international health and biosecurity challenges together, so we can better protect the health of our people, environment, agriculture and industries and our way of life,” Dr Marshall said.
“This, combined with our data science and manufacturing capability in our biological production facility, means we were well prepared to help Australia in One Health with disease identification, prevention and management, to deliver the real world solutions that our nation expects from science.”
CSIRO’s COVID-19 research so far
Current rapid work on COVID-19 spans virus and vaccine:
This article was first published as a CSIRO media release.